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What is Pantoprazole Sodium
Pantoprazole sodium, marketed under the name Protonix, is an organic sodium salt of Pantoprazole. It is a first-generation proton pump inhibitor that brings about a reduction in the amount of acid that is produced in the stomach.
It came into medical use in Germany in 1994. Pantoprazole can be taken orally in the form of either a tablet or a liquid suspension, or it can be administered intravenously (IV). It is available as a generic medication.
Macsen Laboratories is the supplier of high-quality Pantoprazole sodium with ISO certification.
| PRODUCT SPECIFICATIONS | |
|---|---|
| Name of Product | Pantoprazole Sodium |
| IUPAC Name | sodium;5-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]benzimidazol-1-ide |
| Synonyms | Pantoloc; Protonix; Pantecta; Protium; Zurcal; PANTOPRAZOLE SODIUM SALT |
| CAS No | 138786-67-1 |
| Molecular Formula | C16H14F2N3NaO4S |
| Molar Mass | 405.4 g/mol |
| Other available variants | Pantoprazole Sodium Sesquihydrate (164579-32-2) |
| Pubchem CID | 15008962 |
| Pubchem SID | 469688500 |
Chemical Properties
| SR. No | Criteria | Limit/Specification |
|---|---|---|
| 1 | Appearance (Form) | Solid Powder |
| 2 | Appearance (Colour) | White |
| 3 | Melting point (DSC) | 156 °C |
| 4 | Storage Temperature | 2 to 8 °C, dark |
Mechanism of Action
Pantoprazole is a proton pump inhibitor (PPI). It binds to the sulfhydryl group of H+, K+-ATPase, an enzyme responsible for speeding the final step in the acid secretion route. The inactivation of the enzyme inhibits stomach acid output, which in turn relieves acid-related indigestion and heartburn.
Uses
- Pantoprazole is used for short-term treatment of the symptoms of esophagitis (erosion and ulceration of the oesophagus) caused by stomach acid due to gastroesophageal reflux disease for adults and children five years of age and older.
- It may sometimes be combined with antibiotics to treat Helicobacter pylori-caused ulcers.
- It is also used to treat Zollinger-Ellison syndrome (pathological hypersecretory condition).
- It may be used to prevent gastric ulcers in those taking NSAIDs.
Side effects
The common side effects associated with the use of Pantoprazole are as follows:
- Diarrhoea
- Flatulence
- Dizziness, Headache
- Nausea, Vomiting,
- Abdominal pain
- Joint pain
- Injection site reaction
Serious and long-term side effects include:
- Low magnesium levels
- Vitamin B12 deficiency
- Severe diarrhoea
- Bone fractures
- Kidney damage
- Cutaneous lupus erythematosus (CLE)
FAQs
Q. What is Pantoprazole sodium 40 mg used for?
Pantoprazole is a medication that is taken to treat the damage caused by gastroesophageal reflux disease (GERD).
Q. How long does it take for pantoprazole sodium to work?
Within 2-3 days, you should start to feel better. It is possible that you will continue to have some of your symptoms until the pantoprazole fully takes effect, which could take up to four weeks.
Q. Does pantoprazole sodium cause weight gain?
It is possible for you to see a rise in weight while you are taking pantoprazole oral tablets.
Q. Is pantoprazole sodium an antacid?
The proton pump inhibitor, pantoprazole, lowers the quantity of acid that is produced by your stomach.
Buy the best quality Pantoprazole Sodium through Macsen Laboratories.