Home »Speciality Dyes and Biological Stains » Patent Blue V
What is Patent Blue V (Acid Blue 3)
Patent Blue V or Acid Blue 3 is a synthetic triphenylmethane dye. It occurs as dark blue powder or granules. It is principally the calcium or sodium salt of 2-[4-[alpha-(4-diethyl-aminophenyl)-5-hydroxy-2,4-disulfonatophenylmethylidene]-2,5-cyclohexadien-1-ylidene] diethylammonium hydroxide inner salt, and subsidiary colouring matters. It is also called Food Blue 5, Sulphan Blue, Acid Blue 3, L-Blau 3, C-Blau 20, Patentblau V, or Sky Blue C.I. 42051. It is used as a food additive in certain jelly sweets and gelatin desserts in Europe.
Macsen Laboratories is the manufacturer and supplier of high-quality Patent Blue V.
| PRODUCT SPECIFICATIONS | |
|---|---|
| Name of Product | Patent Blue V |
| IUPAC Name | calcium;4-[[4-(diethylamino)phenyl]-(4-diethylazaniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]-6-hydroxybenzene-1,3-disulfonate |
| Synonyms | Acid Blue 3, C.I. Food Blue 5, Carmine Blue V, Acidal Carmine V, Merantine Blue V |
| CAS No | 3536-49-0 |
| Molecular Formula | C54H62CaN4O14S4 |
| Molecular Weight | 1159.4 g/mol |
| Pubchem CID | 77073 |
| Pubchem SID | 463751340 |
Chemical Properties
| SR. No | Criteria | Limit/Specification |
|---|---|---|
| 1 | Appearance (Color) | Dark Blue |
| 2 | Appearance (Form) | Powder or Granules |
| 3 | UV Spectra | Maximum in water at 638 nm at pH 5 |
| 4 | Total Dye Content (percent by mass) | ≥85.0% |
| 5 | Loss on Drying at 135°C | <45% |
| 6 | Water Insoluble matter | >0.2% |
| 7 | Assay | ≥97.0% (HPLC) | 8 | Uses | Food additive, Cosmetic colorant, Dye |
Uses
- Patent Blue V is a dye used in lymphangiography and sentinel node biopsy in medicine to colour lymph vessels.
- It is also used as a stain in dental disclosing tablets to reveal dental plaque on teeth.
- It is useful as a pH indicator for the range 0.8–3.0.
- It is usable as a reversible redox indicator in some analytical methods.
Side effects
Rash, pruritus, erythema, urticaria, angioedema (such as facial oedema or laryngeal oedema), bronchospasm, tachycardia, reduced blood pressure, and circulatory collapse are the most commonly reported consequences in the setting of a hypersensitive reaction associated with the excessive dosage of Patent Blue V.
FAQs
Q. What is the use of Patent Blue V in pharmaceuticals?
Patent Blue V is a sterile injectable dye solution. It is a triphenylmethane dye that is used to reveal vessels in order to improve the imaging of certain vessels in your body.
Q. Is Patent Blue the same as Methylene Blue?
Both Patent Blue and Methylene Blue are used as diagnostic agents for the detection of the sentinel lymph node in breast cancer patients. But in contrast to Patent Blue, Methylene Blue is more widely available and much more cost-effective. Also, Patent Blue poses a greater risk of anaphylaxis and hypersensitivity reactions, thus methylene blue is the preferred choice of agent.
Resources
Food Dyes | An overview of all the dyes currently used in Food
Biological Stains | Classification, Examples & Uses
Buy the best quality Patent Blue V through Macsen Laboratories. We are also the supplier of Sodium salt of Patent Blue. For buying, send us an enquiry-