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What is Gemifloxacin Mesylate
Gemifloxacin mesylate is the mesylate salt of gemifloxacin, which is a naphthyridine and fluoroquinolone derivative, antibacterial agent. It is a quinolone with a broad-spectrum activity used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations, commonly sold under the trade name Factive.
Macsen Laboratories is the supplier of high-quality Gemifloxacin Mesylate with ISO certification.
| PRODUCT SPECIFICATIONS | |
|---|---|
| Name of Product | Gemifloxacin mesylate |
| IUPAC Name | 7-[(4Z)-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;methanesulfonic acid |
| Synonyms | Factive; Gemifloxacin mesilate; Gemifloxacin methanesulfonate; mesilato de gemifloxacina; Gemifloxacina mesilato; Mésylate de gémifloxacine |
| CAS No | 210353-53-0 |
| Molecular Formula | C19H24FN5O7S |
| Molar Mass | 485.5 g/mol |
| Pubchem CID | 9588170 |
| Pubchem SID | 469688493 |
Chemical Properties
| SR. No | Criteria | Limit/Specification |
|---|---|---|
| 1 | Appearance (Form) | Powder |
| 2 | Appearance (Colour) | White to light brown |
| 3 | Solubility (in water) | 10 mg/mL, clear |
| 4 | Storage temp. | Room temperature |
| 5 | Assay | ≥98% (HPLC) |
Uses
- Acute bacterial exacerbation of chronic bronchitis (ABECB) caused by Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, or Moraxella catarrhalis.
- Community-acquired pneumonia (of mild to moderate severity) caused by Streptococcus pneumoniae (including multi-drug resistant strains [MDRSP]), Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, Chlamydia pneumoniae, or Klebsiella pneumoniae.
Side effects
The most common side effects include:
- Nausea and vomiting
- Stomach pain
- Diarrhoea,
- Dizziness and headache
- Rash
The major serious side effects include:
- Central nervous system toxicity
- Cardiovascular toxicity
- Tendon / articular toxicity
- Hepatic toxicity (rare)
FAQs
Q. Is gemifloxacin available in the US?
Due to manufacturing and regulatory concerns, Factive (gemifloxacin) has not been available in the United States in recent years.
Q. Is gemifloxacin a penicillin?
Gemifloxacin belongs to the class of fluoroquinolone antibiotics. It works by eliminating pathogenic microorganisms.
Buy the best quality Gemifloxacin Mesylate through Macsen Laboratories.