What is Sodium azide?
Sodium azide (NaN3) is a sodium salt of hydrazoic acid. It is a white to colorless inorganic compound known for its bacteriostatic properties. It is a conjugate base of hydrazoic acid composed of sodium (Na) and nitrogen (N). It is highly soluble in water and produces a strong-smelling odor after mixing with water. It has the ability to release nitrogen gas, which is why it is used in the synthesis of alcohols and amines.Â
It is commonly used as a preservative for laboratory reagents, stock solutions, diagnostic medicines, herbicides, and fungicides, and is also used as a propellant in inflating automobile airbags.
Macsen Laboratories is the supplier of high-quality Sodium azide.
| PRODUCT SPECIFICATIONS | |
|---|---|
| Name of Product | Sodium azide |
| IUPAC Name | sodium;azide |
| Synonyms | Sodium trinitride; Smite; Azium; Hydrazoic acid sodium salt; Natriumazid; Azoture de sodium; azidosodium; Sodium, azoture de |
| CAS No | 26628-22-8 |
| Molecular Formula | NaN3 |
| Molar Mass | 65.010 g/mol |
| Pubchem CID | 33557 |
| Pubchem SID | 480474277 |
Chemical Properties
| SR. No | Criteria | Limit/Specification |
|---|---|---|
| 1 | Appearance (Form) | Solid Powder, Crystals |
| 2 | Appearance (Color) | Colorless to White |
| 3 | Odor | Odorless |
| 4 | Density | 1.846 g/cm3 |
| 5 | Melting point | 275 °C |
| 6 | Solubility | Highly soluble in ammonia and water Slightly soluble in ethanol and benzene Insoluble in ether, acetone, hexane, chloroform |
| 7 | Solubility (In Water) | 38.9 g/100 mL (0 °C) 40.8 g/100 mL (20 °C) 55.3 g/100 mL (100 °C) |
| 8 | Acidity (pKa) | 4.8 |
| 9 | Decomposition | When heated to decomposition it emits very toxic fumes of nitrogen oxides and disodium oxide |
Uses
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Widely used as a preservative in laboratory reagents and stock solutions.
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Used in enzyme immunoassays (EIA) to prevent the specific colour formation by inhibiting the endogenous peroxidase activity.
- Sodium azide is used as a propellant in automobile air bags as a source to generate gas for airbag inflation.
- It is utilized in organic and inorganic synthesis to introduce the azide functional group, for example, as a reagent in the synthesis of blue fluorescent copolymers, metal phosphonates, and arenes. It also works as a precursor to other inorganic azide compounds, such as lead azide and silver azide.
- It is an antimicrobial preservative for biochemical solutions as well as a helpful probing reagent in biochemistry.
- Sodium azide is a bacteriostatic preservative that is extensively used to preserve biological specimens. It shows bacteriostatic properties by acting as a a nitridizing agent and by inhibiting oxidative phosphorylation in some species of bacteria.
- In agriculture, it is used for pest control of soil-borne pathogens such as Meloidogyne incognita or Helicotylenchus dihystera and as a mutagen for crop selection of plants such as rice, barley or oats.
Toxicity (Side effects)
Sodium azide is fatally toxic, and even minute quantities can induce symptoms. It results in extrapyramidal symptoms in addition to necrosis of the cerebral cortex, cerebellum, and basal ganglia. Hypotension, blindness, and hepatic necrosis may also be the symptoms of toxicity.
Faqs
Is sodium azide a good antifungal?
Sodium azide is a toxic compound, and it is not used as an antifungal. Sodium azide is mainly used as a preservative in aqueous laboratory reagents and biological fluids, blood samples and a fixative for tissue.Â
What is sodium azide used for?
Sodium azide is used in industry and as a preservative in laboratory reagents and stock solutions. It’s also most common in enzyme immunoassays (EIA) and is also used in the synthesis of alcohols and amines due to its nitrogen release property.
What is the function of sodium azide in a buffer?
Sodium azide acts as a preservative and inhibits microbial growth in the buffer by restricting cytochrome c oxidase, catalase, and peroxidase, which helps in maintaining biological samples.
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