What is Acriflavine Powder
Acriflavine powder is a fluorescent dye that can be applied to the skin as a topical antiseptic and is also used in biological staining. It occurs as a brownish-orange powder. Acriflavine was discovered in 1912 as a byproduct of coal tar by Paul Ehrlich, and its first application was during WWI for treating parasites that caused sleeping sickness. It is known to be effective for parasitic infection treatment. It is also used to treat external fungal infections in aquarium fish, as well as minor wounds, burns, and infected skin.
You can buy cGMP manufactured Acriflavine HCl Powder from us in packing sizes ranging from 5 gm, 20 gm, 100 gm, 500 gm, 1 Kg & 25 Kg.
No MOQs, several payment options and discounted rates are available for bulk purchase.
To know more, send us your details here.
Macsen Laboratories is a GMP & ISO certified manufacturer & supplier of high-quality Acriflavine BPC.
| PRODUCT IDENTIFIERS | |
|---|---|
| Name of Product | Acriflavine HCl |
| Synonyms | Chromoflavine; Neutroflavine; Xanthacridine; Acriflavon; Trypaflavine; Gonacrine; Gonacrin; Panflavin; Acriflavina |
| CAS No | 8063-24-9 |
| Molecular Formula | C27H28Cl4N6 |
| Molecular Weight | 578.4 g/mol |
| Other Grade | Acriflavine Extra Pure |
| Pubchem CID | 53393742 |
| Pubchem SID | 462730480 |
| GMP | ✓ |
| DMF | ✓ |
MAC FLAVINE – Pharmaceutical grade Acriflavine Hydrochloride
(Available in 5 gm, 20gm, 100 gm packaging)
• Full compliance with specifications of BPC (British Pharmaceutical Codex)
• Ultra-High Purity
• Minimum 99.5% assay
• cGMP Manufactured
• Free from Metals, Organic Impurities and Solvents
• Shipping Worldwide
The product will be packed in food-grade HDPE Jars. This product is shipped in powder form and you can mix it with water for preparing a solution (0.1%, 1%, 2%). Each shipment will be provided with a Batch Certificate of Analysis.
Our Specifications
| SR. No | Criteria | Limit/Specification | Our Results |
|---|---|---|---|
| 1 | Description | Orange- Red to Red Crystalline Powder, Odourless, Taste Acid |
Orange- Red to Red Crystalline Powder, Odourless. |
| 2 | Solubility | Must Pass B.P.C-63 Test | Passes B.P.C-63 Test |
| 3 | Identification | Must Pass 1 to 5 B.P.C-63 Tests | Passes 1 to 5 B.P.C-63 Tests |
| 4 | Water Insoluble Matter Test | Must Pass B.P.C-63 Test | Passes B.P.C-63 Test |
| 5 | Certain Other Acridine Derivative Test | Must Pass B.P.C-63 Test | Passes B.P.C-63 Test |
| 6 | Water | NMT6.5% | 3-4% |
| 7 | Sulphated Ash Test | NMT 1.0% | 0.5-0.8 % |
| 8 | Assay (With Reference To Anhydrous Subs. & As % Of C14h14n3cl) | MINIMUM 98.5% TO 105.0% MAXIMUM | 99.5-103.5% |
SAFETY INFORMATION
Symbol: GHS07
Signal Word: Danger
Hazard Statements: H302, H315, H318, H332
Flash Point (C): Not applicable
For buying Acriflavine, send us an enquiry-
Uses of Acriflavine
- Acriflavine is a fluorescent labelling agent for high molecular weight RNA in biochemistry.
- It is also being researched since 2014 as an antimalarial drug.
- It was also used to treat gonorrhoea but was later replaced by antibiotics.
- It is still used as a topical antiseptic for treating contaminated or suppurating (weeping) wounds.
Acriflavine in Veterinary
Acriflavine has a long history of application in the treatment, and prevention of illnesses that affect fish. Acriflavine in aquaculture is used in the treatment and prevention of the diseases of fish such as Columnaris Infections, Velvet and Ich infections, Saprolegnia spp. Infections, Fin and egg rot infections, for the disinfection of fish eggs, treatment of open wounds, and treatment of external protozoan infections.
Because of the antiseptic properties of Acriflavine, it is also used in the form of a topical cream for treating fungal infections in animals such as dogs, cattle and pigs.
Side effects
Commonly associated negative effects with Acriflavine-containing drugs are as below:
- Vomiting
- Dizziness
- Nausea
- Headache
- When used for fish, Acriflavine is believed to cause infertility and can be stressful for many fishes at a high dosage.
This isn’t a complete list. Although some of the side effects are rare, others are dangerous. Contact your doctor if you have any of the side symptoms, especially if they persist.
Precautions
Before using Acriflavine, tell your doctor about all of your current prescriptions, over-the-counter goods (such as vitamins and herbal supplements), allergies, pre-existing disorders, and current health issues (e.g., pregnancy, upcoming surgery, etc.). If you have certain medical problems, you may be more sensitive to the drug’s negative effects. Follow your doctor’s instructions or the product insert’s instructions. The dosage is fixed by your medical condition. Contact your doctor if any of your issues persists or worsens.
FAQs
Q. Is Acriflavine habit-forming or addictive?
Most medicines are free of the risk of addiction or abuse. Medications that can be addictive are usually classified as controlled substances by the government. In India, schedule H or X is an example, while in the United States, schedule II-V is an example. Acri is not reported as a controlled substance in almost all countries except Australia where it is considered either a Schedule 5 (Caution) or Schedule 7 (Dangerous Poison) substance.
Q. Is acriflavine safe for fish?
Acriflavine can be used as a short term bucket dip for fish, or it can be added to the aquarium water to treat the entire tank, preventing higher dosage as it may be stressful for many fish. Also, it severely damages live plants and stains artificial plants and other decorations in the tank.
Q. How to use acriflavine for fish?
Acriflavine can be used as a short term (5 minutes to 1 hour) or long term bath (3 days to 3 weeks) for fish or it can be added to the aquarium water to treat the entire tank. Topical application is sometimes used on wounds to help prevent bacterial infection.
Q. Where to buy Acriflavine?
Macsen Laboratories is a GMP and ISO-certified manufacturer and supplier of various grades of high-quality Acriflavine.